Selected Publications

Divito S, Cherpes TL, Hendricks RL. A triple entente: virus, neurons, and CD8+ T cells maintain HSV-1 latency. Immunol Res. 2006;36(1-3):119-26.

Divito SJ, Hendricks RL. Activated inflammatory infiltrate in HSV-1-infected corneas without herpes stromal keratitis. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1488-95.

Frank GM*, Divito SJ*, Maker DM, Xu M, Hendricks RL A novel p40-independent function of IL-12p35 is required for progression and maintenance of herpes stromal keratitis. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3591-8. *Co-first author.

Divito, S.J., et al. Endogenous dendritic cells mediate the effects of intravenously injected therapeutic immunosuppressive dendritic cells in transplantation. Blood. 2010 Oct;116(15):2694-705.

Divito, SJ. Morelli, AE., Larregina, AT. Role of neurokinin-1 receptor in the initiation and maintenance of skin chronic inflammatory diseases. Immunol Res. 2011 Aug;50(2-3):195-201.

Montecalvo, A., Larregina, A.T., Shufesky, W.J., Stolz, D.B., Sullivan, M.L.G., Karlsson, J.M., Baty, C.J., Gibson, G.A., Erdos, G., Wang, Z., Milosevic, J., Tkacheva, O., Divito, S.J., et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood. 2012 Jan;119(3):756-66.

Wang, Z., Divito, S.J., et al. Dendritic cell (DC) therapies in transplantation revisited: Deletion of conventional DCs deters the effect of therapeutic tolerogenic DCs. Am J Transplant. 2012 Jun;12(6):1398-408.

Sheu, J.*, Divito, S.J.*, et al. Mosaic focal dermal hypoplasia caused by a novel somatic mutation in PORCN detected by fibroblast culture of affected skin. Br J Dermatol. 2015 Aug;173(2):568-570. *Co-first authors.

Liu, Q., Rojas-Canales, D.M., Divito, S.J., et al. Donor dendritic cell-derived exosomes promote allograft-targeting immune response. J Clin Invest. 2016 Aug;126(8):2805-2820.

Zhuang, Q., Liu, Q., Divito, S.J., et al. Graft-infiltrating host dendritic cells play a key role in organ transplant rejection. Nat Commun. 2016 Aug;7:12623.

Pan, Y.D. Tian, T., Park, C.O., Lofftus, S.Y., Mei, S.L., Liu, X., Luo, C., O’Malley, J.T., Gehad, A., Teague, J.E., Divito, S.J., et al. Tissue resident memory T cell survival requires exogenous lipid uptake and metabolism. Nature. 2017 Mar;543(7644):252-256.

De Masson, A., O’Malley, J.T., Elco, C.P., Garcia, S.S., Divito, S.J., et al. High-throughput sequencing of the T cell receptor b gene identifies aggressive early-stage Mycosis Fungoides. Sci Transl Med.

Griffin, R.L., Kupper, T.S., Divito, S.J. Humanized mice in dermatology research. J Invest Dermatol. 2015 Dec;135(12):e39-43.

Romar, G.A., Kupper, T.S., Divito, S.J. Research techniques made simple: Techniques to assess cell proliferation. J Invest Dermatol. 2016 Jan;136(1):e1-7.

Divito, S.J. and Kupper, T.S. Inhibiting Janus kinases to treat alopecia areata. Nat Med. 2014 Sep;20(9):989-90.

Stern, R.S. and Divito, S.J. Stevens-Johnson syndrome and Toxic epidermal necrolysis: Associations, outcomes, and pathobiology-Thirty years of progress but still much to be done. J Invest Dermatol. 2017 May;137(5):1004-1008.

Divito SJ. Screening HLA to Prevent Severe Drug Reactions-A Devil’s Advocate Perspective. JAMA Dermatol. 2019 Jun 1;155(6):655-656.

Divito SJ. Implementation of Genetic Screening to Prevent Severe Cutaneous Adverse Drug Reactions is Crucial-Rebuttal From the Devil’s Antagonist – Reply. JAMA Dermatol. 2020 Feb 1;156(2):221-222.

Li DJ, Romar GA, Hsieh PC, Wells M, Foreman RK, Lian CG, Divito SJ. Histologic features of GVHD-associated angiomatosis: Insights into pathophysiology and treatment. J Am Acad Dermatol. 2020

Divito SJ, Aasebo AT, Matos TR, Hsieh PC, Collin M, Elco CP, O’Malley JT, Bækkevold ES, Reims HM, Gedde-Dahl T, Hagerstrom M, Hilaire J, Lian JW, Milford EL, Pinkus GS, Ho VT, Soiffer RJ, Kim HT, Mihm MC Jr, Ritz J, Guleria I, Cutler CS, Clark R, Jahnsen FL, Kupper TS. Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host-disease. J Clin Invest. 2020

Comment: Young, JW. Alternative mechanisms that mediate graft-versus-host-disease in allogeneic hematopoietic cell transplants. J Clin Invest. 2020 Sept 1;130(9):4532-4535

Schunkert EM, Shah PN, Divito SJ. Skin Resident Memory T Cells May Play Critical Role in Delayed-Type Drug Hypersensitivity Reactions. Front Immunol. 2021 Aug 23;12:654190.

Schunkert EM and Divito SJ. Updates and Insights in the Diagnosis and Management of DRESS Syndrome. Curr Dermatol Rep. 2021;10(4):192-204.

Wang CW, Divito SJ, Chung WH, Hung SI. Advances in the Pathomechanisms of Delayed Drug Hypersensitivity. Immunol Allergy Clin North Am. 2022 May;42(2):357-373.

Phillips EJ, Bouchard CS, Divito SJ. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis-Coordinating Research Priorities to Move the Field Forward. JAMA Dermatol. 2022 Jun 1;158(6):607-608.

Chimbetete T, Buck C, Choshi P, Chebet R, Pedretti S, Divito SJ, Phillips E, Lehloenya R, Peter J. HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity. J Investigative Dermatol. In Press.

Coromilas A. Divito SJ, Phillips EJ, Micheletti R. Physical and Mental Health Impact of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and Post Hospital Discharge Care: Identifying Practice Gaps. JAAD International. 2023 Jan 30;11:88-89.

Li DJ, Velasquez GA, Romar GA, Schunkert EM, Foreman RK, Divito SJ. Assessment of Need for Improved Identification of a Culprit Drug in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis. JAMA Dermatol. 2023 Jun 21:e231693

Lee GH, Guzman AK, Divito SJ, Soiffer RJ, Silk AW, Schmults CD. Cutaneous Squamous-Cell Carcinoma after Treatment with Ruxolitinib or Belumosudil. N Engl J Med. 2023 Jul 13;389(2):188-190.

Marks ME, Botta RK, Abe R, Beachkofsky TM, Boothman I, Carleton BC, Chung WH, Cibotti RR, Dodiuk-Gad RP, Grimstein C, Hasegawa A, Hoofnagle JH, Hung SI, Kaffenberger B, Kroshinsky D, Lehloenya RJ, Martin-Pozo M, Micheletti RG, Mockenhaupt M, Nagao K, Pakala S, Palubinsky A, Pasieka HB, Peter J, Pirmohamed M, Reyes M, Saeed HN, Shupp J, Sukasem C, Syu JY, Ueta M, Zhou L, Chang WC, Becker P, Bellon T, Bonnet K, Cavalleri G, Chodosh J, Dewan AK, Dominguez A, Dong X, Ezhkova E, Fuchs E, Goldman J, Himed S, Mallal S, Markova A, McCawley K, Norton AE, Ostrov D, Phan M, Sanford A, Schlundt D, Schneider D, Shear N, Shinkai K, Tkaczyk E, Trubiano JA, Volpi S, Bouchard CS, Divito SJ, Phillips EJ. Updates in SJS/TEN: collaboration, innovation, and community. Front Med (Lausanne). 2023 Oct 11;10:1213889.

Brüggen MC, Walsh S, Ameri MM, Anasiewicz N, Maverakis E, French LE, Ingen-Housz-Oro S; DRESS Delphi consensus group; Abe R, Ardern-Jones M, Assier H, Barbaud A, Bensaid B, Bernal W, Bernier C, Brassard A, Brezinová E, Cabañas R, Cardones A, Chu CY, Chua SL, Descamps V, Didona B, Divito SJ, Dodiuk-Gad R, Elman S, Gaspar K, Mortz CG, Hama N, Lee HY, Horváth B, Jörg L, Kaffenberger BH, Kucinskiene V, Lebrun-Vignes B, Lehloenya RJ, Meyersburg D, Micheletti R, Milpied B, Miyagawa F, Mostaghimi A, Nägeli M, Naldi L, Oppel E, Phillips EJ, Pirani T, Ranki A, Mälkönen T, Rosenbach M, Salavastru C, Staumont-Salle D, Sandberg H, Setterfield J, Shinkai K, Shiohara T, Soria A, Tartar D, Tiplica GS, Traidl S, Vorobyev A, von Wachter C, Worswick S, Cho YT. Management of Adult Patients with Drug Reaction with Eosinophilia and Systemic Symptoms: A Delphi-Based International Consensus. JAMA Dermatol. 2024 Jan 1;160(1):37-44.

Shah PN, Romar GA, Manukyan A, Ko W-C, Hsieh P-C, Velasquez GA, Schunkert EM, Fu X, Guleria I, Bronson RT, Wei K, Waldman AH, Vleugels FR, Liang MG, Giobbie-Hurder A, Mostaghimi A, Schmidt BAR, Barrera V, Foreman RK, Garber M, Divito SJ. Systemic and skin-limited delayed-type drug hypersensitivity reactions associate with distinct resident and recruited T cell subsets. J Clin Invest. 2024. In Press.